Kurumi Tokisaki's powerful time manipulation abilities are rendered useless against Giorno's Gold Experience Requiem, which has the ability to return any action back to zero. This means that Kurumi's time rewinding and freezing techniques would be completely nullified. Additionally, Giorno's life-giving abilities would give him the upper hand in terms of healing and recovery during the battle. Finally, GER's sentience allows it to act independently, giving Giorno an edge in strategic planning. In the end, Giorno's ultimate stand power would prove too much for Kurumi to handle.